Use of SGLT2 inhibitors in cardiovascular diseases: why, when and how?

The authors present an up-to-date narrative literature review of the physiological mechanisms of action, current indications, therapeutic utility and side effects of SGLT2 inhibitors.

Understanding the mechanisms of placebo and nocebo effects

The placebo effect represents an elegant model to understand how the brain works. It is worth knowing that there is not a single but many placebo effects, with different mechanisms across different systems, medical conditions and therapeutic interventions.

Data protection and biomedical research in Switzerland: setting the record straight

The objective of this article is to review the interaction of data protection law and biomedical research with a predominant focus on the Swiss context.

PedAMINES: a disruptive mHealth app to tackle paediatric medication errors

Medication errors are among the most common medical adverse events and an important cause of patient morbidity and mortality, affecting millions of people worldwide each year. This problem is especially acute in paediatric settings, where most drugs given intravenously to children are provided in vials prepared for the adult population.

Candida auris – recommendations on infection prevention and control measures in Switzerland

Candida auris, a globally emerging pathogen, has been repeatedly introduced into European healthcare settings, leading to large and long-lasting nosocomial outbreaks. The pathogen has already been isolated in Switzerland, requiring clinicians and microbiologists to become alert.

Including adolescents of childbearing potential in clinical trials with possible exposure to teratogenic medication: a challenge for paediatricians and researchers

This article reviews how to address practical and ethical questions regarding minor adolescents of childbearing potential enrolled in a clinical trial that may involve teratogenic medication and offers a series of concrete advice and tools for dealing with problematic situations.

Value of the TTM risk score for early prognostication of comatose patients after out-of-hospital cardiac arrest in a Swiss university hospital

Since the TTM followed strict inclusion and exclusion criteria, the validity in a general ICU population of cardiac arrest patients is unknown. With this study, the authors aimed to confirm and assess the usefulness in a Swiss population suffering from out-of-hospital cardiac arrest outside a clinical trial.

Attitudes and acceptance of patients undergoing visceral surgery towards an open access electronic medical record – a Swiss-German single-centre study

The question of whether patients should have electronic access to their data has become one of the key topics under discussion.

The new remuneration system TARPSY in Swiss psychiatric hospitals: effects on length of stay and readmissions?

If being evident at all, the effects of the new remuneration system TARPSY on LOS and readmission rates seem to be small. Concerns that declining daily rates in TARPSY would result in early discharges and increased readmission rates did not prove true in adult and geriatric psychiatry.

Supplmentum 245: Annual Congress of the Swiss Society of Rheumatology