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Viewpoint

Vol. 149 No. 2930 (2019)

Non-invasive diagnosis of liver steatosis: ready for primetime?

  • Nicolas Goossens
DOI
https://doi.org/10.4414/smw.2019.20108
Cite this as:
Swiss Med Wkly. 2019;149:w20108
Published
22.07.2019

References

  1. European Association for the Study of the Liver (EASL), European Association for the Study of Diabetes (EASD), European Association for the Study of Obesity (EASO). EASL-EASD-EASO Clinical Practice Guidelines for the management of non-alcoholic fatty liver disease. J Hepatol. 2016;64(6):1388–402. doi:.https://doi.org/10.1016/j.jhep.2015.11.004
  2. Hagström H, Nasr P, Ekstedt M, Hammar U, Stål P, Hultcrantz R, et al. Fibrosis stage but not NASH predicts mortality and time to development of severe liver disease in biopsy-proven NAFLD. J Hepatol. 2017;67(6):1265–73. doi:.https://doi.org/10.1016/j.jhep.2017.07.027
  3. Younossi ZM, Koenig AB, Abdelatif D, Fazel Y, Henry L, Wymer M. Global epidemiology of nonalcoholic fatty liver disease-Meta-analytic assessment of prevalence, incidence, and outcomes. Hepatology. 2016;64(1):73–84. doi:.https://doi.org/10.1002/hep.28431
  4. Pimpin L, Cortez-Pinto H, Negro F, Corbould E, Lazarus JV, Webber L, et al.; EASL HEPAHEALTH Steering Committee. Burden of liver disease in Europe: Epidemiology and analysis of risk factors to identify prevention policies. J Hepatol. 2018;69(3):718–35. doi:.https://doi.org/10.1016/j.jhep.2018.05.011
  5. Sasso M, Beaugrand M, de Ledinghen V, Douvin C, Marcellin P, Poupon R, et al. Controlled attenuation parameter (CAP): a novel VCTE™ guided ultrasonic attenuation measurement for the evaluation of hepatic steatosis: preliminary study and validation in a cohort of patients with chronic liver disease from various causes. Ultrasound Med Biol. 2010;36(11):1825–35. doi:.https://doi.org/10.1016/j.ultrasmedbio.2010.07.005
  6. Baumeler S, Jochum W, Neuweiler J, Bergamin I, Semela D. Controlled attenuation parameter for the assessment of liver steatosis in comparison with liver histology: a single-centre real life experience. Swiss Med Wkly. 2019;149:w20077. doi:.https://doi.org/10.4414/smw.2019.20077
  7. Pu K, Wang Y, Bai S, Wei H, Zhou Y, Fan J, et al. Diagnostic accuracy of controlled attenuation parameter (CAP) as a non-invasive test for steatosis in suspected non-alcoholic fatty liver disease: a systematic review and meta-analysis. BMC Gastroenterol. 2019;19(1):51. doi:.https://doi.org/10.1186/s12876-019-0961-9
  8. Thiele M, Rausch V, Fluhr G, Kjærgaard M, Piecha F, Mueller J, et al. Controlled attenuation parameter and alcoholic hepatic steatosis: Diagnostic accuracy and role of alcohol detoxification. J Hepatol. 2018;68(5):1025–32. doi:.https://doi.org/10.1016/j.jhep.2017.12.029
  9. Kwok R, Choi KC, Wong GL-H, Zhang Y, Chan HL-Y, Luk AO-Y, et al. Screening diabetic patients for non-alcoholic fatty liver disease with controlled attenuation parameter and liver stiffness measurements: a prospective cohort study. Gut. 2016;65(8):1359–68. doi:.https://doi.org/10.1136/gutjnl-2015-309265
  10. Ginès P, Graupera I, Lammert F, Angeli P, Caballeria L, Krag A, et al. Screening for liver fibrosis in the general population: a call for action. Lancet Gastroenterol Hepatol. 2016;1(3):256–60. doi:.https://doi.org/10.1016/S2468-1253(16)30081-4

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