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Short communication

Vol. 142 No. 2526 (2012)

Daptomycin for highly resistant Enterococcus faecium infection

  • Christiane Rosin
  • Christine Bernsmeier
  • José M. Entenza
  • Philippe Moreillon
  • Reno Frei
  • Maja Weisser
  • Ursula Flückiger
Cite this as:
Swiss Med Wkly. 2012;142:w13603


We report a case series of 11 patients with severe E. faeciuminfections treated with daptomycin. All strains were resistant to ampicillin (MIC >8 mg/l), but susceptible to vancomycin. Seven out of 11 strains were also highly resistant to gentamicin (MIC >500 mg/l). All patients were treated with multiple broad-spectrum antibiotics prior to isolation of E. faecium and had severe underlying diseases. Our experience suggests that salvage therapy with daptomycin might be a safe and efficacious treatment for E. faecium infections.


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