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Special article

Vol. 153 No. 8 (2023)

Medical-ethical guidelines: Living donation of solid organs

  • Swiss Academy of Medical Sciences
Cite this as:
Swiss Med Wkly. 2023;153:40126


No abstract available.


  1. Abecassis MM, Fisher RA, Olthoff KM, Freise CE, Rodrigo DR, Samstein B, et al.; A2ALL Study Group. Complications of living donor hepatic lobectomy—a comprehensive report. Am J Transplant. 2012 May;12(5):1208–17. 10.1111/j.1600-6143.2011.03972.x DOI:
  2. Achermann R, Koller M, De Geest S, Hadaya K, Müller TF, Huynh-Do U, et al.; The Psychosocial Interest Group And The Swiss Transplant Cohort Study. Demographic, psychosocial and health disparities between living and deceased renal allograft recipients in Switzerland. Swiss Med Wkly. 2021 Aug;151(3132):w20532. 10.4414/smw.2021.20532 DOI:
  3. Benzing C, Schmelzle M, Oellinger R, Gruettner K, Muehlisch AK, Raschzok N, et al. Living-Donor Liver Transplant: An Analysis of Postoperative Outcome and Health-Related Quality of Life in Liver Donors. Exp Clin Transplant. 2018 Oct;16(5):568–74.
  4. Bjerre A, Mjøen G, Line PD, Naper C, Reisaeter AV, Åsberg A. Five decades with grandparent donors: the Norwegian strategy and experience. Pediatr Transplant. 2020 Sep;24(6):e13751. 10.1111/petr.13751 DOI:
  5. Bruintjes MH, van Helden EV, de Vries M, Wirken L, Evers AW, van Middendorp H, et al. Chronic pain following laparoscopic living-donor nephrectomy: prevalence and impact on quality of life. Am J Transplant. 2019 Oct;19(10):2825–32. 10.1111/ajt.15350 DOI:
  6. Bugeja A, Shams I, Harris S, Clark EG, Burns KD, Sood MM, et al. Cannabis and Cigarette Use Before and After Living Kidney Donation. Can J Kidney Health Dis. 2021 Feb;8:2054358121997243. 10.1177/2054358121997243Crossref returns an apparently incorrect page number: "Bugeja, Shams, Harris, Clark, Burns, Sood, et al., 2021"The page range was updated but differs from the author's original: 1–9. (Ref. "Bugeja, Shams, Harris, Clark, Burns, Sood, et al., 2021")Edifix has not found an issue number in the journal reference. Please check the volume/issue information. (Ref. "Bugeja, Shams, Harris, Clark, Burns, Sood, et al., 2021") DOI:
  7. Burkhalter F, Huynh-Do U, Hadaya K, Matter M, Müller T, Binet I, et al. Early complications after living donor nephrectomy: analysis of the Swiss Organ Living Donor Health Registry. Swiss Med Wkly. 2017 Aug;147:w14497. 10.4414/smw.2017.14497Edifix has not found an issue number in the journal reference. Please check the volume/issue information. (Ref. "Burkhalter, Huynh-Do, Hadaya, Matter, et al., 2017") DOI:
  8. Butt Z, Dew MA, Liu Q, Simpson MA, Smith AR, Zee J, et al. Psychological Outcomes of Living Liver Donors From a Multicenter Prospective Study: Results From the Adult-to-Adult Living Donor Liver Transplantation Cohort Study2 (A2ALL-2). Am J Transplant. 2017 May;17(5):1267–77. 10.1111/ajt.14134 DOI:
  9. Butt Z, DiMartini AF, Liu Q, Simpson MA, Smith AR, Zee J, et al. Fatigue, Pain, and Other Physical Symptoms of Living Liver Donors in the Adult-to-Adult Living Donor Liver Transplantation Cohort Study. Liver Transpl. 2018 Sep;24(9):1221–32. 10.1002/lt.25185 DOI:
  10. Cheah YL, Simpson MA, Pomposelli JJ, Pomfret EA. Incidence of death and potentially life-threatening near-miss events in living donor hepatic lobectomy: a world-wide survey. Liver Transpl. 2013 May;19(5):499–506. 10.1002/lt.23575 DOI:
  11. Dew MA, Dabbs AD, Myaskovsky L, Shyu S, Shellmer DA, DiMartini AF, et al. Meta-analysis of medical regimen adherence outcomes in pediatric solid organ transplantation. Transplantation. 2009 Sep;88(5):736–46. 10.1097/TP.0b013e3181b2a0e0 DOI:
  12. Dew MA, DiMartini AF, Ladner DP, Simpson MA, Pomfret EA, Gillespie BW, et al. Psychosocial Outcomes 3 to 10 Years After Donation in the Adult to Adult Living Donor Liver Transplantation Cohort Study. Transplantation. 2016 Jun;100(6):1257–69. 10.1097/TP.0000000000001144 DOI:
  13. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004 Aug;240(2):205–13. 10.1097/ DOI:
  14. DiMartini A, Cruz RJ Jr, Dew MA, Fitzgerald MG, Chiappetta L, Myaskovsky L, et al. Motives and decision making of potential living liver donors: comparisons between gender, relationships and ambivalence. Am J Transplant. 2012 Jan;12(1):136–51. 10.1111/j.1600-6143.2011.03805.x DOI:
  15. Emond JC, Fisher RA, Everson G, Samstein B, Pomposelli JJ, Zhao B, et al. Changes in liver and spleen volumes after living liver donation: a report from the Adult-to-Adult Living Donor Liver Transplantation Cohort Study (A2ALL). Liver Transpl. 2015 Feb;21(2):151–61. 10.1002/lt.24062 DOI:
  16. Ghobrial RM, Freise CE, Trotter JF, Tong L, Ojo AO, Fair JH, et al.; A2ALL Study Group. Donor morbidity after living donation for liver transplantation. Gastroenterology. 2008 Aug;135(2):468–76. 10.1053/j.gastro.2008.04.018 DOI:
  17. Gorgen A, Goldaracena N, Zhang W, Rosales R, Ghanekar A, Lilly L, et al. Surgical Complications after Right Hepatectomy for Live Liver Donation: Largest Single-Center Western World Experience. Semin Liver Dis. 2018 May;38(2):134–44. 10.1055/s-0038-1636932 DOI:
  18. Grams ME, Sang Y, Levey AS, Matsushita K, Ballew S, Chang AR, et al.; Chronic Kidney Disease Prognosis Consortium. Kidney-Failure Risk Projection for the Living Kidney-Donor Candidate. N Engl J Med. 2016 Feb;374(5):411–21. 10.1056/NEJMoa1510491 DOI:
  19. Holtzman S, Clarke HA, McCluskey SA, Turcotte K, Grant D, Katz J. Acute and chronic postsurgical pain after living liver donation: incidence and predictors. Liver Transpl. 2014 Nov;20(11):1336–46. 10.1002/lt.23949 DOI:
  20. Ibrahim HN, Foley R, Tan L, Rogers T, Bailey RF, Guo H, et al. Long-term consequences of kidney donation. N Engl J Med. 2009 Jan;360(5):459–69. 10.1056/NEJMoa0804883 DOI:
  21. Lentine KL, Kasiske BL, Levey AS, Adams PL, Alberú J, Bakr MA, et al. Summary of Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Care of Living Kidney Donors. Transplantation. 2017 Aug;101(8):1783–92. 10.1097/TP.0000000000001770 DOI:
  22. Matas AJ, Rule AD. Long-term Medical Outcomes of Living Kidney Donors. Mayo Clin Proc. 2022 Nov;97(11):2107–22. 10.1016/j.mayocp.2022.06.013 DOI:
  23. Muzaale AD, Massie AB, Wang MC, Montgomery RA, McBride MA, Wainright JL, et al. Risk of end-stage renal disease following live kidney donation. JAMA. 2014 Feb;311(6):579–86. 10.1001/jama.2013.285141 DOI:
  24. Rein JL. The nephrologist’s guide to cannabis and cannabinoids. Curr Opin Nephrol Hypertens. 2020 Mar;29(2):248–57. 10.1097/MNH.0000000000000590 DOI:
  25. Ringe B, Strong RW. The dilemma of living liver donor death: to report or not to report? Transplantation. 2008 Mar;85(6):790–3. 10.1097/TP.0b013e318167345e DOI:
  26. Ross LF, Rodrigue JR, Veatch RM. Ethical and Logistical Issues Raised by the Advanced Donation Program “Pay It Forward” Scheme. J Med Philos. 2017 Oct;42(5):518–36. 10.1093/jmp/jhx018 DOI:
  27. Ruckle D, Keheila M, West B, Baron P, Villicana R, Mattison B, et al. Should donors who have used marijuana be considered candidates for living kidney donation? Clin Kidney J. 2018 Nov;12(3):437–42. 10.1093/ckj/sfy107 DOI:
  28. Soliman KM, Daoud A, Posadas Salas MA, Rice T, Uehara G, Shayto R, et al. Accepting Living Kidney Donors with Preexisting Diabetes Mellitus: A Perspective on the Recent OPTN Policy Change-July 2022. Clin J Am Soc Nephrol. 2023 Jan;18(1):127–9. 10.2215/CJN.09460822 DOI:
  29. Takagi K, Umeda Y, Yoshida R, Watanabe N, Kuise T, Yoshida K, et al. Short-term and long-term outcomes in living donors for liver transplantation: cohort study. Int J Surg. 2020 Dec;84:147–53. 10.1016/j.ijsu.2020.11.013Edifix has not found an issue number in the journal reference. Please check the volume/issue information. (Ref. "Takagi, Umeda, Yoshida, Watanabe, Kuise, Yoshida, et al., 2020") DOI:
  30. Thiel GT, Nolte C, Tsinalis D, Steiger J, Bachmann LM. Investigating kidney donation as a risk factor for hypertension and microalbuminuria: findings from the Swiss prospective follow-up of living kidney donors. BMJ Open. 2016 Mar;6(3):e010869. 10.1136/bmjopen-2015-010869 DOI:
  31. Thys K, Borry P, Schotsmans P, Dobbels F. Should minors and young adults qualify as potential live kidney donors? The views of international transplant professionals. Pediatr Transplant. 2019 Sep;23(6):e13526. 10.1111/petr.13526 DOI:
  32. Trotter JF, Gillespie BW, Terrault NA, Abecassis MM, Merion RM, Brown RS Jr, et al.; Adult-to-Adult Living Donor Liver Transplantation Cohort Study Group. Laboratory test results after living liver donation in the adult-to-adult living donor liver transplantation cohort study. Liver Transpl. 2011 Apr;17(4):409–17. 10.1002/lt.22246 DOI: