Skip to main navigation menu Skip to main content Skip to site footer

Original article

Vol. 151 No. 4142 (2021)

Open aneurysm repair in patients with concomitant abdominal aortic aneurysm and aorto-iliac occlusive disease is associated with a high mortality and surgical complication rate

  • Sabine Richarz
  • Soheila Aghlmandi
  • Andrei Zdoroveac
  • Alexandra Müller
  • Andrej Isaak
  • Lorenz Gürke
  • Thomas Wolff
DOI
https://doi.org/10.4414/SMW.2021.w30050
Cite this as:
Swiss Med Wkly. 2021;151:w30050
Published
19.10.2021

Summary

AIM OF THE STUDY: To evaluate whether the outcome after open aneurysm repair combined with aorto-femoral bypass in patients with concomitant abdominal aortic aneurysm (AAA) and aorto-iliac occlusive disease (AIOD) is inferior to open aneurysm repair for isolated AAA or aorto-femoral bypass for isolated AIOD.

METHODS: We performed a retrospective analysis of 30-day mortality, 1-year mortality and surgical complications of consecutive patients undergoing elective aneurysm repair, aorto-femoral bypass or a combination of these at two vascular surgery departments from 2003 to 2013. Potential risk factors were investigated by multivariable analysis.

RESULTS: Overall, 511 patients underwent open repair for isolated AAA, 104 aorto-femoral bypass for isolated AIOD and 46 open AAA repair combined with aorto-femoral bypass for concomitant AAA and AIOD. Surgical complications occurred in 17% of AAA, 23% of AIOD and 37% of combined patients (odds ratio [OR] combined vs AAA 2.76, 95% confidence interval [CI] 1.43–5.34; p = 0.003). Colon ischaemia occurred in 3.7% of AAA, 2.9% of AIOD and 13% of combined patients (incicidence rate ratio [IRR] combined vs AAA 3.27, 95% CI 1.37–7.81; p = 0.01). The 30-day mortality was 3.1% in AAA, 4.8% in AIOD, and 11% in combined patients (IRR combined vs AAA 3.17, 95% CI 1.26–7.96; p = 0.01). One-year mortality was 5.7% in AAA, 5.8% in AIOD and 15% in combined patients (IRR combined vs AAA 2.50, 95% CI 1.17–5.35; p = 0.02).

CONCLUSIONS: Combined AAA repair and aorto-femoral bypass has a significantly higher 30-day mortality and postoperative complication rate than isolated AAA repair. Patients with concomitant AAA and AIOD thus represent a high-risk population, which should be considered when deciding on the indication for AAA treatment.

References

  1. Biancari F, Leo E, Ylönen K, Vaarala MH, Rainio P, Juvonen T. Value of the Glasgow Aneurysm Score in predicting the immediate and long-term outcome after elective open repair of infrarenal abdominal aortic aneurysm. Br J Surg. 2003 Jul;90(7):838–44. https://doi.org/10.1002/bjs.4130
  2. McPhee JT, Hill JS, Eslami MH. The impact of gender on presentation, therapy, and mortality of abdominal aortic aneurysm in the United States, 2001-2004. J Vasc Surg. 2007 May;45(5):891–9. https://doi.org/10.1016/j.jvs.2007.01.043
  3. Brady AR, Fowkes FG, Greenhalgh RM, Powell JT, Ruckley CV, Thompson SG. Risk factors for postoperative death following elective surgical repair of abdominal aortic aneurysm: results from the UK Small Aneurysm Trial. On behalf of the UK Small Aneurysm Trial participants. Br J Surg. 2000 Jun;87(6):742–9. https://doi.org/10.1046/j.1365-2168.2000.01410.x
  4. Bayly PJ, Matthews JN, Dobson PM, Price ML, Thomas DG. In-hospital mortality from abdominal aortic surgery in Great Britain and Ireland: Vascular Anaesthesia Society audit. Br J Surg. 2001 May;88(5):687–92. https://doi.org/10.1046/j.0007-1323.2001.01778.x
  5. Bredahl K, Jensen LP, Schroeder TV, Sillesen H, Nielsen H, Eiberg JP. Mortality and complications after aortic bifurcated bypass procedures for chronic aortoiliac occlusive disease. J Vasc Surg. 2015 Jul;62(1):75–82. https://doi.org/10.1016/j.jvs.2015.02.025
  6. Daniel VT, Gupta N, Raffetto JD, McPhee JT. Impact of coexisting aneurysms on open revascularization for aortoiliac occlusive disease. J Vasc Surg. 2016 Apr;63(4):944–8. https://doi.org/10.1016/j.jvs.2015.10.062
  7. Bisgaard J, Gilsaa T, Rønholm E, Toft P. Aortic aneurysm disease vs. aortic occlusive disease: differences in outcome and intensive care resource utilisation after elective surgery: an observational study. Eur J Anaesthesiol. 2013 Feb;30(2):65–72. https://doi.org/10.1097/EJA.0b013e32835b9d7b
  8. Costin JA, Watson DR, Duff SB, Edmonson-Holt A, Shaffer L, Blossom GB. Evaluation of the complexity of open abdominal aneurysm repair in the era of endovascular stent grafting. J Vasc Surg. 2006 May;43(5):915–20. https://doi.org/10.1016/j.jvs.2006.01.017
  9. Dindo D, Demartines N, Clavien PA. Classification of surgical complications: a new proposal with evaluation in a cohort of 6336 patients and results of a survey. Ann Surg. 2004 Aug;240(2):205–13. https://doi.org/10.1097/01.sla.0000133083.54934.ae
  10. Dovzhanskiy DI, Bischoff MS, Wilichowski CD, Rengier F, Klempka A, Böckler D. Outcome analysis and risk factors for postoperative colonic ischaemia after aortic surgery. Langenbecks Arch Surg. 2020 Nov;405(7):1031–8. https://doi.org/10.1007/s00423-020-01964-2
  11. Williamson JS, Ambler GK, Twine CP, Williams IM, Williams GL. Elective Repair of Abdominal Aortic Aneurysm and the Risk of Colonic Ischaemia: Systematic Review and Meta-Analysis. Eur J Vasc Endovasc Surg. 2018 Jul;56(1):31–9. https://doi.org/10.1016/j.ejvs.2018.03.005
  12. Landry GJ, Liem TK, Abraham CZ, Jung E, Moneta GL. Predictors of perioperative morbidity and mortality in open abdominal aortic aneurysm repair. Am J Surg. 2019 May;217(5):943–7. https://doi.org/10.1016/j.amjsurg.2018.12.054
  13. Dillavou ED, Muluk SC, Makaroun MS. A decade of change in abdominal aortic aneurysm repair in the United States: have we improved outcomes equally between men and women? J Vasc Surg. 2006 Feb;43(2):230–8. https://doi.org/10.1016/j.jvs.2005.09.043
  14. Beck AW, Goodney PP, Nolan BW, Likosky DS, Eldrup-Jorgensen J, Cronenwett JL ; Vascular Study Group of Northern New England. Predicting 1-year mortality after elective abdominal aortic aneurysm repair. J Vasc Surg. 2009 Apr;49(4):838–43. https://doi.org/10.1016/j.jvs.2008.10.067
  15. Deery SE, Lancaster RT, Baril DT, Indes JE, Bertges DJ, Conrad MF, et al. Contemporary outcomes of open complex abdominal aortic aneurysm repair. J Vasc Surg. 2016 May;63(5):1195–200. https://doi.org/10.1016/j.jvs.2015.12.038
  16. Dubois L, Durant C, Harrington DM, Forbes TL, Derose G, Harris JR. Technical factors are strongest predictors of postoperative renal dysfunction after open transperitoneal juxtarenal abdominal aortic aneurysm repair. J Vasc Surg. 2013 Mar;57(3):648–54. https://doi.org/10.1016/j.jvs.2012.09.043
  17. Chong T, Nguyen L, Owens CD, Conte MS, Belkin M. Suprarenal aortic cross-clamp position: a reappraisal of its effects on outcomes for open abdominal aortic aneurysm repair. J Vasc Surg. 2009 Apr;49(4):873–80. https://doi.org/10.1016/j.jvs.2008.10.057
  18. Senekowitsch C, Assadian A, Assadian O, Hartleb H, Ptakovsky H, Hagmüller GW. Replanting the inferior mesentery artery during infrarenal aortic aneurysm repair: influence on postoperative colon ischemia. J Vasc Surg. 2006 Apr;43(4):689–94. https://doi.org/10.1016/j.jvs.2005.12.016

Most read articles by the same author(s)