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Review article: Biomedical intelligence

Vol. 142 No. 4344 (2012)

Diagnostic errors and flaws in clinical reasoning: mechanisms and prevention in practice

  • Mathieu Nendaz
  • Arnaud Perrier
DOI
https://doi.org/10.4414/smw.2012.13706
Cite this as:
Swiss Med Wkly. 2012;142:w13706
Published
21.10.2012

Summary

Diagnostic errors account for more than 8% of adverse events in medicine and up to 30% of malpractice claims. Mechanisms of errors may be related to the working environment but cognitive issues are involved in about 75% of the cases, either alone or in association with system failures. The majority of cognitive errors are not related to knowledge deficiency but to flaws in data collection, data integration, and data verification that may lead to premature diagnostic closure. This paper reviews some aspects of the literature on cognitive psychology that help us to understand reasoning processes and knowledge organisation and summarises biases related to clinical reasoning. It reviews the strategies described to prevent cognitive diagnostic errors. Many approaches propose awareness and reflective practice during daily activities, but the improvement of the quality of training at the pre-graduate, postgraduate and continuous levels, by using evidence-based education, should also be considered. Several conditions must be fulfilled to increase the understanding, the prevention, and the correction of diagnostic errors related to clinical reasoning: physicians must be willing to understand their own reasoning and decision processes; training efforts should be provided during the whole continuum of a clinician’s career; and the involvement of medical schools, teaching hospitals, and medical societies in medical education research should be increased to improve evidence about error prevention.

References

  1. Blendon RJ, DesRoches CM, Brodie M, Benson JM, Rosen AB, Schneider E, et al. Views of practicing physicians and the public on medical errors. N Engl J Med. 2002;347(24):1933–40.
  2. Berner ES, Graber ML. Overconfidence as a cause of diagnostic error in medicine. Am J Med. 2008;121(5 Suppl):S2–23.
  3. Gandhi TK, Kachalia A, Thomas EJ, Puopolo AL, Yoon C, Brennan TA, et al. Missed and delayed diagnoses in the ambulatory setting: a study of closed malpractice claims. Ann Intern Med. 2006;145(7):488–96.
  4. Schiff GD, Hasan O, Kim S, Abrams R, Cosby K, Lambert BL, et al. Diagnostic error in medicine: analysis of 583 physician-reported errors. Arch Intern Med. 2009;169(20):1881–7.
  5. Graber ML, Franklin N, Gordon R. Diagnostic error in internal medicine. Arch Intern Med. 2005;165(13):1493–9.
  6. Nendaz M. Medical education and quality of decision-making: Is there an evidence-based relationship? Rev Med Interne. 2011;32(7):436–42.
  7. Nendaz M, Charlin B, Leblanc V, Bordage G. Le raisonnement clinique: données issues de la recherche et implications pour l’enseignement. Ped Med. 2005;6:235–54.
  8. Nendaz MR, Gut AM, Perrier A, Louis-Simonet M, Blondon-Choa K, Herrmann FR, et al. Beyond clinical experience: features of data collection and interpretation that contribute to diagnostic accuracy. J Gen Intern Med. 2006;21(12):1302–5.
  9. Elstein AS. Thinking about diagnostic thinking: a 30-year perspective. Adv Health Sci Educ Theory Pract. 2009;14(Suppl 1):7–18.
  10. Norman G. Research in clinical reasoning: past history and current trends. Med Educ. 2005;39(4):418–27.
  11. Bordage G. Prototypes and semantic qualifiers: from past to present. Med Educ. 2007;41(12):1117–21.
  12. Charlin B, Tardif J, Boshuizen HP. Scripts and medical diagnostic knowledge: theory and applications for clinical reasoning instruction and research. Acad Med. 2000;75(2):182–90.
  13. Schmidt HG, Norman GR, Boshuizen HP. A cognitive perspective on medical expertise: theory and implications. Acad Med. 1990;65(10):611–21.
  14. Chang RW, Bordage G, Connell KJ. The importance of early problem representation during case presentations. Acad Med. 1998;73(10 Suppl):S109–11.
  15. Pelaccia T, Tardif J, Triby E, Charlin B. An analysis of clinical reasoning through a recent and comprehensive approach: the dual-process theory. Med Educ Online. 2011;16.
  16. Norman G. Dual processing and diagnostic errors. Adv Health Sci Educ Theory Pract. 2009;14(Suppl 1):37–49.
  17. Norman GR, Eva KW. Diagnostic error and clinical reasoning. Med Educ. 2010;44(1):94–100.
  18. Ark TK, Brooks LR, Eva KW. The benefits of flexibility: the pedagogical value of instructions to adopt multifaceted diagnostic reasoning strategies. Med Educ. 2007;41(3):281–7.
  19. Norman G, Young M, Brooks L. Non-analytical models of clinical reasoning: the role of experience. Med Educ. 2007;41(12):1140–5.
  20. Lucchiari C, Pravettoni G. Cognitive balanced model: a conceptual scheme of diagnostic decision making. J Eval Clin Pract. 2011;18(1):82–8.
  21. Brooks LR, LeBlanc VR, Norman GR. On the difficulty of noticing obvious features in patient appearance. Psychol Sci. 2000;11(2):112–7.
  22. Bordage G. Why did I miss the diagnosis? Some cognitive explanations and educational implications. Acad Med. 1999;74(10 Suppl):S138–43.
  23. Zwaan L, Thijs A, Wagner C, van der Wal G, Timmermans DR. Relating faults in diagnostic reasoning with diagnostic errors and patient harm. Acad Med. 2012;87(2):149–56.
  24. Kahneman D, Slovic P, Tversky A. Judgment Under Uncertainty: heuristics and biases. Cambridge, UK: Cambridge University Press 1982.
  25. Elstein A, Schwartz A, Nendaz M. Medical decision making. In: Norman G, van der Vleuten C, Newble D, eds. International Handbook of Research in Medical Education. Boston: Kluwer 2002:231–62.
  26. Junod A. Décision médicale ou la quête de l’explicite. Genève: Médecine et Hygiène 2007.
  27. Gorini A, Pravettoni G. An overview on cognitive aspects implicated in medical decisions. Eur J Intern Med. 2011;22(6):547–53.
  28. Croskerry P. The importance of cognitive errors in diagnosis and strategies to minimize them. Acad Med. 2003;78(8):775–80.
  29. Croskerry P. Clinical cognition and diagnostic error: applications of a dual process model of reasoning. Adv Health Sci Educ Theory Pract. 2009;14(Suppl 1):27–35.
  30. Graber ML. Educational strategies to reduce diagnostic error: can you teach this stuff? Adv Health Sci Educ Theory Pract. 2009;14(Suppl 1):63–9.
  31. Croskerry P. Cognitive forcing strategies in clinical decisionmaking. Ann Emerg Med. 2003;41(1):110–20.
  32. Hall KH. Reviewing intuitive decision-making and uncertainty: the implications for medical education. Med Educ. 2002;36(3):216–24.
  33. Sherbino J, Dore KL, Siu E, Norman GR. The effectiveness of cognitive forcing strategies to decrease diagnostic error: an exploratory study. Teach Learn Med. 2011;23(1):78–84.
  34. Coderre S, Wright B, McLaughlin K. To think is good: querying an initial hypothesis reduces diagnostic error in medical students. Acad Med. 2010;85(7):1125–9.
  35. Ely JW, Graber ML, Croskerry P. Checklists to reduce diagnostic errors. Acad Med. 2011;86(3):307–13.
  36. Mamede S, Schmidt HG. The structure of reflective practice in medicine. Med Educ. 2004;38(12):1302–8.
  37. Mamede S, Schmidt HG, Rikers RM, Penaforte JC, Coelho-Filho JM. Influence of perceived difficulty of cases on physicians’ diagnostic reasoning. Acad Med. 2008;83(12):1210–6.
  38. Mamede S, Schmidt HG, Penaforte JC. Effects of reflective practice on the accuracy of medical diagnoses. Med Educ. 2008;42(5):468–75.
  39. Mamede S, van Gog T, van den Berge K, Rikers RM, van Saase JL, van Guldener C, et al. Effect of availability bias and reflective reasoning on diagnostic accuracy among internal medicine residents. JAMA. 2010;304(11):1198–203.
  40. Aronson L. Twelve tips for teaching reflection at all levels of medical education. Med Teach. 2011;33(3):200–5.
  41. Kassirer JP. Teaching clinical medicine by iterative hypothesis testing. Let’s preach what we practice. N Engl J Med. 1983;309(15):921–3.
  42. Nendaz MR, Gut AM, Louis-Simonet M, Perrier A, Vu NV. Bringing explicit insight into cognitive psychology features during clinical reasoning seminars: a prospective, controlled study. Educ Health (Abingdon). 2011;24(1):496.
  43. Yudkowsky R, Otaki J, Lowenstein T, Riddle J, Nishigori H, Bordage G. A hypothesis-driven physical examination learning and assessment procedure for medical students: initial validity evidence. Med Educ. 2009;43(8):729–40.
  44. Hatala RM, Brooks LR, Norman GR. Practice makes perfect: the critical role of mixed practice in the acquisition of ECG interpretation skills. Adv Health Sci Educ Theory Pract. 2003;8(1):17–26.
  45. Nendaz MR, Bordage G. Promoting diagnostic problem representation. Med Educ. 2002;36(8):760–6.
  46. Dornan T, Littlewood S, Margolis SA, Scherpbier A, Spencer J, Ypinazar V. How can experience in clinical and community settings contribute to early medical education? A BEME systematic review. Med Teach. 2006;28(1):3–18.
  47. Littlewood S, Ypinazar V, Margolis SA, Scherpbier A, Spencer J, Dornan T. Early practical experience and the social responsiveness of clinical education: systematic review. BMJ. 2005;331(7513):387–91.
  48. Rudaz A, Gut AM, Louis-Simonet M, Perrier A, Vu NV, Nendaz MR. Acquisition of clinical competence: added value of clerkship real-life contextual experience. Med Teach. 2012:e1–e6.
  49. Harden RM, Grant J, Buckley G, Hart IR. Best evidence medical education. Adv Health Sci Educ Theory Pract. 2000;5(1):71–90.
  50. Steinert Y, Mann K, Centeno A, Dolmans D, Spencer J, Gelula M, et al. A systematic review of faculty development initiatives designed to improve teaching effectiveness in medical education: BEME Guide No. 8. Med Teach. 2006;28(6):497–526.

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