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Review article: Biomedical intelligence

Vol. 140 No. 3738 (2010)

Primary testicular lymphoma

  • A Zouhair
  • E Herrmann
  • G Ugurluer
  • M Ozsahin
  • PM Gaye
  • RO Mirimanoff
DOI
https://doi.org/10.4414/smw.2010.13076
Cite this as:
Swiss Med Wkly. 2010;140:w13076
Published
13.09.2010

Summary

Primary testicular lymphoma (PTL) is a rare disease accounting for 1% of non-Hodgkin’s lymphoma. PTL occurs more frequently in older patients and is a potentially fatal disease. In the early stages (I and II), the treatment consists of orchidectomy followed by chemotherapy (CT) and prophylactic scrotal radiotherapy (RT) with/or without iliac and/or paraaortic lymph node RT. In the advanced stages (III and IV), CT is the treatment of choice whereas the place of scrotal RT is controverted. In both early and advanced disease intrathecal CT is warranted to prevent CNS relapse. New molecular approaches and/or more aggressive treatments are being explored.

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