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Careful preparation of submission documents by the investigators and close adherence to formal and legal requirements have the potential to considerably optimise and expedite the ethics committee review process, and thus the commencement of the clinical research.
One in seven Swiss physicians has left patient care - results from a national cohort study from 1980-2009
Physician shortage is problematic, but the percentage of physicians who have left patient care in Switzerland is unclear.
The diagnostic diversity index can be seen as an indicator of diagnostic precision - the higher the degree of diversity, the better the diagnostic precision.
Rationale and methods of an observational study to support the design of a nationwide surgical registry: the MIDAS study
Surgical registries are becoming increasingly popular, and Swiss legislation requires data on therapeutic outcome quality. The Swiss Association of Surgeons has agreed on a first minimum data set for a nationwide registry.
A digitally facilitated citizen-science driven approach accelerates participant recruitment and increases study population diversity
Conventional clinical studies have a number of shortcomings such as restictive exclusion criteria and failure to address patient-relevant outcomes. Recent developments in society and technology could help to overcome some of these problems.
External validation of the 80+ score and comparison with three clinical scores identifying patients at least 75 years old at risk of unplanned readmission within 30 days after discharge
A potentially avoidable readmission is an unplanned readmission occurring within 30 days of discharge. As 20% of hospitalised elderly patients are rehospitalised as an unplanned readmission, it is necessary to identify those at risk.
Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders
Premature discontinuation occurs in about 25% of randomised clinical trials in Switzerland; it mainly affects investigator-initiated trials and is mostly due to problems with recruitment of patients.
Could it be that legislators and other public health professional base their tobacco control policy decisions on smoking prevalence estimates that are more reassuring than may be justified?
Estimating the incidence of traumatic spinal cord injuries in Switzerland: Using administrative data to identify potential coverage error in a cohort study
Administrative data are routinely collected in many high-resource countries and offer a wealth of information related to health, but interpretation of these data must take into account its limitations in terms of incomplete, biased coverage.