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The findings presented here suggest that the course of COVID-19 is not necessarily ominous in the presence of a compromised immune response and tend to reinforce the emerging therapeutic concepts of a controlled mitigation of the immune cascade following SARS CoV-2 infection.
The assessment of pulmonary congestion remains one of the more difficult routine tasks in chest radiology, and there are few publications concerning signs of pulmonary oedema on computed tomography (CT).
The sensitivity and specificity of the mannitol bronchial challenge test to identify asthma in different populations: a systematic review
Several studies have investigated the accuracy of the mannitol test to identify asthma. However, the results from these studies differ substantially.
Chronic rhinosinusitis in unified airway disease: surfactant proteins as mediators of respiratory immunity
Management of chronic rhinosinusitis and asthma must be jointly carried out as one functional entity.
Health-related quality of life and stress-related post-transplant trajectories of lung transplant recipients: a three-year follow-up of the Swiss Transplant Cohort Study
Lung transplantation provides a viable option for the survival of end-stage lung diseases. Besides survival as a clinical outcome measure, health-related quality of life and psychological distress have become important study outcomes.
Vocal cord dysfunction is characterised by paradoxical inspiratory laryngeal motion and is often misdiagnosed as asthma. Diagnosis is difficult, because laryngoscopy is positive only during symptomatic episodes or provocation tests.
Sarcoidosis is a disorder of unknown aetiology. It usually responds to steroids, but side-effects and steroid-resistance may require other treatments. Endothelin has in-vitro fibrogenic activity and the endothelin system is activated in sarcoidosis.
In the ICU, the main challenges with obese patients are to take into account the pulmonary pathophysiological characteristics when choosing the best management options.
Use of venovenous extracorporeal membrane oxygenation avoids some of the risks associated with intubation and mechanical ventilation. But it is necessary to weigh the risks and benefits before using it in morbid obesity.