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Association of allostatic load with health-related quality of life in patients with arterial hypertension: a cross-sectional analysis
Allostatic load, a marker of cumulative stress, is associated with higher morbidity and mortality, and reduced health-related quality of life in healthy adults. In patients with hypertension this association has not been investigated.
Pipamperone and delirium: a preliminary evaluation of its effectiveness in the management of delirium and its subtypes
Delirium is an underdiagnosed and undermanaged syndrome, with substantial prevalence and potentially deleterious consequences. Despite its frequent use in the management of delirium, the effectiveness of pipamperone has not yet been evaluated.
Tramadol has a triple action all of which are relevant in treating psychic suffering, especially suffering from the feelings of psychic “pain” that can arise from social loss. As it is short acting, has a wide therapeutic range as a weak mu-receptor agonist, has a relatively low risk for inducing neurochemical tolerance, and comparatively low risk for abuse, tramadol needs to be further evaluated for the treatment of depression.