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Iatrogenic events contributing to paediatric intensive care unit admission

Original article
Salvini R, Frey B
Swiss Med Wkly. 2021;151:w20414

In the case series presented here, the number of PICU admissions associated with iatrogenic events was significant and comparable to adult data on admission to ICU caused by iatrogenic events. The categories with most potential for improvement are nosocomial infections and the wrong management decisions / delayed diagnoses. Focused measures on these iatrogenic events may have a major impact on patient outcome, availability of PICU resources and healthcare costs.

Beware the inhaled steroids or corticophobia?

Review article: Biomedical intelligence
Gidaris DK, Stabouli S, Bush A
Swiss Med Wkly. 2021;151:w20450

Inhaled corticosteroids have been the cornerstone of atopic, allergic asthma management for more than half a century. They have side effects (as does every medication), but they have transformed the control of asthma and saved many lives since their introduction. The current review revisits local and systemic side effects of inhaled corticosteroids and explores the prevalence and nature of parental fears (“corticophobia”) in different parts of the world. The empathetic physician treating asthma should bear in mind the impact of parental concerns on the management of this potentially life-threatening disease and try to dispel myths at every opportunity by emphasising the well-established benefits and excellent safety profile of inhaled corticosteroids.

A retrospective epidemiological study of paediatric femoral fractures

Original article
Valaikaite R, Tabard-Fougère A, Steiger C, Samara E, Dayer R, Ceroni D
Swiss Med Wkly. 2020;150:w20360

Femoral fracture is a significant major trauma in children and adolescents, sometimes resulting in serious complications. This study aimed to determine the epidemiology of femoral fractures and to define associated injuries and mortality incidence in a pediatric population below 16 years old.

Renal replacement therapy in children and adolescents

Leumann E
Swiss Med Wkly. 2020;150:w20371

This Viewpoint article discusses a study recently published in Swiss Medical Weekly that describes the incidence of end stage renal disease, the primary diagnosis, modalities of renal replacement therapy and long-term outcomes in patients up to 20 years of age, as well as some aspects that differ from renal disease in adults.

Serum lactate at 24 hours is associated with outcome in children requiring extracorporeal membrane oxygenation for pulmonary causes – a retrospective, observational study

Original article
Amodeo A, Erdil T, Vanetta C, Steigmiller K, Schmiady M, Schweiger M, Pretre R, Dave H
Swiss Med Wkly. 2020;150:w20358

Extracorporeal membrane oxygenation (ECMO) has become an essential life-saving tool. Being resource-intensive, judicious use and optimising the outcomes of this precious resource is important. This retrospective, explanatory, observational study aimed to quantify associations between factors and outcome after pulmonary ECMO in children.

Healthcare professionals’ opinions on psychological screening in follow-up care for childhood cancer survivors

Original article
Harju E, Hendriks MJ, Roser K, Michel G
Swiss Med Wkly. 2020;150:w20356

There is overall agreement that screening for psychological late effects is not yet standard in follow-up care in Switzerland. It is important to mitigate perceived barriers and concerns of healthcare professionals to enable a successful implementation of psychological distress screening according to the established standards of care.

Including adolescents of childbearing potential in clinical trials with possible exposure to teratogenic medication: a challenge for paediatricians and researchers

Review article: Medical guidelines
Michaud PA, Diezi M, Guihard L, Jacot-Guillarmod M, Kleist P, Sprumont D, Wenger P
Swiss Med Wkly. 2020;150:w20333

This article reviews how to address practical and ethical questions regarding minor adolescents of childbearing potential enrolled in a clinical trial that may involve teratogenic medication and offers a series of concrete advice and tools for dealing with problematic situations.

PedAMINES: a disruptive mHealth app to tackle paediatric medication errors

Review article: Biomedical intelligence
Ehrler F, Siebert JN
Swiss Med Wkly. 2020;150:w20335

Medication errors are among the most common medical adverse events and an important cause of patient morbidity and mortality, affecting millions of people worldwide each year. This problem is especially acute in paediatric settings, where most drugs given intravenously to children are provided in vials prepared for the adult population.

Neonatal transport in Switzerland: a retrospective single-centre analysis – quo vadis?

Original article
Leemann T, Bernet V, Grass B, Hagmann C
Swiss Med Wkly. 2020;150:w20308

The high proportion of urgent transfers emphasises the need for an efficient neonatal transport system and dedicated neonatal transport teams staffed by members with training in neonatal transport and expertise in handling neonatal emergencies.

Do fathers care about their own immunisation status? The Child-Parent-Immunisation Survey and a review of the literature

Original article
Erb ML, Erlanger TE, Heininger U
Swiss Med Wkly. 2020;150:w20289

This is the first study to analyse the complete immunisation status of fathers of young children. It is often incomplete with potentially missed opportunities for updating vaccinations during recent physician consultations. 

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