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Gestational trophoblastic disease in Switzerland: retrospective study of the impact of a regional reference centre

Original article
Fehlmann A, Benkortbi K, Rosseel G, Meyer-Hamme U, Tille JC, Sloan-Bena F, Paoloni-Giacobino A, Rougemont AL, Bodmer A, Botsikas D, Mathevet P, Petignat P, Undurraga Malinverno M
Swiss Med Wkly. 2021;151:w20406

The European Society of Medical Oncology recommends that countries should have reference centres to provide adequate diagnosis and treatment of gestational trophoblastic disease. This study reflects the activity of the Swiss trophoblastic disease centre from the French-speaking part of Switzerland created in 2009, and its role as local and national reference centre, in terms of global health, for women with gestational trophoblastic disease.

Use of valproate in pregnancy and in women of childbearing age between 2014 and 2018 in Switzerland: a retrospective analysis of Swiss healthcare claims data

Original article
Spoendlin J, Blozik E, Graber S, Rauch M, Marxer C, Rüegg S, Meier C, Winterfeld U, Panchaud A
Swiss Med Wkly. 2021;151:w20386

As in most other European countries, the use of valproate in women of childbearing age in this study was higher than what the authors estimated to be indicated. This study demonstrates the value of electronic claims databases in the evaluation of drug exposure during pregnancy.

Maternal mortality in Switzerland 2005–2014

Original article
Perotto L, Zimmermann R, Quack Lötscher KC
Swiss Med Wkly. 2020;150:w20345

The trend of reducing direct maternal mortality as well as lethality after caesarean section continues. Haemorrhage is still the leading cause of direct maternal mortality. Indirect maternal mortality is increasing and specifically suicides need special attention.

Labour outcomes with defibulation at delivery in immigrant Somali and Sudanese women with type III female genital mutilation/cutting

Original article
Rouzi AA, Berg RC, Al-Wassia H, Alamoudi R, Hariri W, Sindi G, Almansouri N, Sahly N
Swiss Med Wkly. 2020;150:w20326

Defibulation at delivery is an effective minor surgical procedure that should be in the armamentarium of the healthcare providers managing women with type III female genital mutilation/cutting.

Medical-ethical recommendations: preimplantation genetic testing PGT

Special article
Swiss Academy of Medical Sciences
Swiss Med Wkly. 2020;150:w20298

The recommendations of the Swiss Academy of Medical Sciences (SAMS) are designed to draw attention, from an ethical perspective, to important aspects of the PGT counselling and decision-making situation, and to promote ethical awareness in the performance of PGT. In addition, they discuss how, for example, surplus information should be managed.

High prevalence of severe vitamin D deficiency during the first trimester in pregnant women in Switzerland and its potential contributions to adverse outcomes in the pregnancy

Original article
Christoph P, Challande P, Raio L, Surbek D
Swiss Med Wkly. 2020;150:w20238

The current recommendations of vitamin D supplementation of 600 IU in pregnant women are insufficient, and novel strategies seem mandatory, potentially leading to improved maternal health and benefits to children’s long-term health in Switzerland and worldwide.

Guideline of the Swiss Society of Gynaecology and Obstetrics (SSGO) on acute and recurrent urinary tract infections in women, including pregnancy

Review article: Medical guidelines
Betschart C, Albrich WC, Brandner S, Faltin D, Kuhn A, Surbek D, Geissbuehler V
Swiss Med Wkly. 2020;150:w20236

This guideline from the Swiss Society of Gynaecology and Obstetrics provides quick answers for every day clinical questions concerning urinary tract infections, especially for obstetricians and gynaecologists.

Video analysis for the evaluation of vaginal births

Hamza A
Swiss Med Wkly. 2018;148:w14658

Video analysis for the evaluation of vaginal births: a comment

Pecks U, Alkatout I
Swiss Med Wkly. 2018;148:w14654

The great strength of video technology lies in providing information about medical knowledge and practice. For the benefit of the patient, new technical achievements should be implemented in concepts of continuing medical education.

Is breastfeeding an equipoise option in effectively treated HIV-infected mothers in a high-income setting?

Review article: Biomedical intelligence
Kahlert C, Aebi-Popp K, Bernasconi E, Martinez de Tejada B, Nadal D, Paioni P, Rudin C, Staehelin C, Wagner N, Vernazza P
Swiss Med Wkly. 2018;148:w14648

Low rates of mother-to-child transmission of HIV via breast milk whilst mothers are on cART in low-resource settings question whether a recommendation to abstain from breastfeeding in high-income countries is still justified.

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