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Iron overload associated symptoms and laboratory changes in the Swiss Haemochromatosis Cohort – when a clinician should become attentive

Original article
Kölmel S, Nowak A, Krayenbuehl PA
Swiss Med Wkly. 2020;150:w20294

Elevated ALT levels and metacarpophalangeal arthropathy remained independently associated with elevated ferritin levels in patients with haemochromatosis and should prompt clinicians to consider iron overload in patients with hereditary haemochromatosis.

Insulin under the influence of light

Review article: Biomedical intelligence
Ursino G, Coppari R
Swiss Med Wkly. 2020;150:w20273

Recent evidence suggests that photic inputs regulate diurnal variations in the insulin sensitivity of metabolically relevant tissues via a previously unrecognised mechanism involving the ventromedial hypothalamic nucleus. Therefore, understanding the mechanisms underlying photic control of insulin action is of paramount medical importance.

Heavy energy drink consumption is associated with risky substance use in young Swiss men

Original article
Benkert R, Abel T
Swiss Med Wkly. 2020;150:w20243

Chronic heavy energy drink consumers are a significant population subgroup in Switzerland and are relevant for public health due to the co-occurrence of unhealthy substance use.

Individualised nutritional support in medical inpatients – a practical guideline

Viewpoint
Ballmer PE
Swiss Med Wkly. 2020;150:w20245

The significance of malnutrition in medical patients in hospitals has finally been recognised, and malnutrition has become an independent diagnosis. This is relevant not only for the care of patients but also economically, and as such is of paramount importance in health care.

Individualised nutritional support in medical inpatients – a practical guideline

Review article: Medical guidelines
Baumgartner A, Kägi-Braun N, Tribolet P, Gomes F, Stanga Z, Schuetz P
Swiss Med Wkly. 2020;150:w20204

Recent trials have demonstrated that early, individualised nutritional support improves clinical outcomes of patients. Hence, we must now think of clinical nutrition as a medical treatment that has a measurable impact on disease development and recovery.

Glycaemic patterns in healthy elderly individuals and in those with impaired glucose metabolism – exploring the relationship with nonglycaemic variables

Original article
Medina Escobar P, Sakem B, Risch L, Risch M, Grebhardt C, Nydegger UE, Stanga Z
Swiss Med Wkly. 2019;149:w20163

This study relates the glycation gap to lipid metabolism, low grade inflammation as evidenced by high-sensitivity C-reactive protein, and kidney function as estimated by glomerular filtration rates.

Evidence-based nutrition for the malnourished, hospitalised patient: one bite at a time

Review article: Biomedical intelligence
Merker M, Gomes F, Stanga Z, Schuetz P
Swiss Med Wkly. 2019;149:w20112

Malnutrition is highly prevalent in the inpatient setting, particularly in older patients with multiple morbidities, but the medical community struggles to find efficient, evidence-based approaches for its prevention and treatment.

Effects of maternal caffeine consumption on the breastfed child: a systematic review

Systematic review
McCreedy A, Bird S, Brown LJ, Shaw-Stewart J, Chen YF
Swiss Med Wkly. 2018;148:w14665

Caffeine is a central nervous system stimulant occurring naturally in some foods and used to treat primary apnoea in premature babies. However, high caffeine intake can be harmful, and caffeine is transmitted into breastmilk.

Vitamin D levels in Swiss breast cancer survivors

Original article
Baumann M, Dani SU, Dietrich D, Hochstrasser A, Klingbiel D, Mark MT, Riesen WF, Ruhstaller T, Templeton AJ, Thürlimann B
Swiss Med Wkly. 2018;148:w14576

Cholecalciferol (vitamin D3) is widely supplemented in breast cancer survivors because of the role of vitamin D in multiple health outcomes, but usual supplementation regimens appear to be inadequate in many cases.

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