Topic Collection Search
Allergy and immunology
Complementary medicine and alternative therapies
Critical care / intensive care
Dentistry / oral medicine
Geriatric medicine / aging
Haematology / blood transfusion
History of medicine
Legal and forensic medicine
Nutrition and metabolism
Obstetrics and gynaecology
Occupational and environmental medicine
Organisation of health care
Otolaryngology / head and neck surgery
Pharmacology and therapeutics
Primary care, family medicine
Psychiatry and psychotherapy
Quality of care
Statistics and research methods
The cellular prion protein (PrPC), a cell surface glycoprotein originally identified for its central role in prion diseases, has recently been implicated in the pathogenesis of other neurodegenerative disorders, such as Alzheimer’s and Parkinson’s diseases. This article provides an overview of what is known about the role of PrPC beyond prion disorders and discusses the potential implications of targeting this protein in different diseases.
With the technical developments in neurosurgery, increasing numbers of neurosurgical implants are used in an increasingly aged population of patients with several comorbidities. Consequently, the number of neurosurgical implant-associated infections is continuously raising.
Decades of research in affective neuroscience have been devoted to identifying the underlying neuropsychological mechanisms that can lead to compulsive reward-seeking behaviours where the amount of effort mobilised to obtain an outcome is no longer justified by its value.
Interventional psychiatry in the management of behavioural and psychological symptoms of dementia: a qualitative review
Pharmaceutical options for the treatment of behavioural and psychological symptoms of dementia (BPSD) are limited. This article invetigates the potential role of interventional techniques, considering the possible overlapping role of specific neurocircuits underlying BPSD.
In recent years, there has been a revival in research on hallucinogenic drugs. One of the most interesting questions is how the typical effects of LSD are represented on a neuronal level. This question was recently addressed by three clinical trials.
Significant strides have been made in developing and refining psychotherapeutic treatments. However, there is significant room to improve them, and they may benefit from innovations such as extracellular matrix modification.
The goal of this review is to highlight the multiple challenges involved in the development of sensory neuroprostheses, the current state of the technology, and to briefly discuss future clinical and research prospects.
Primary brainstem haemorrhages remain associated with poor outcomes compared to other forms of spontaneous intracranial haemorrhage. Their management needs re-evaluation and reinvestigation to update the relevant data.
Now in Swiss Medical Weekly, dementia care in general practice is examined from the perspective of GPs. The study by Giezendanner et al. is important, shining a light on an increasingly pressing area of primary care and identifying gaps in knowledge, confidence and healthcare services.