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Acetylcholinesterase inhibitors combined with memantine for moderate to severe Alzheimer's disease: a meta-analysis
The clinical efficacy and safety of combination therapy with acetylcholinesterase inhibitors (AChEI) and memantine compared to AChEIs or memantine alone in patients with Alzheimer’s disease is inconclusive.
Rationale and methods of an observational study to support the design of a nationwide surgical registry: the MIDAS study
Surgical registries are becoming increasingly popular, and Swiss legislation requires data on therapeutic outcome quality. The Swiss Association of Surgeons has agreed on a first minimum data set for a nationwide registry.
Caffeine is a central nervous system stimulant occurring naturally in some foods and used to treat primary apnoea in premature babies. However, high caffeine intake can be harmful, and caffeine is transmitted into breastmilk.
The aim of video documentation during labour is to provide an observational tool for obstetric care by midwives and obstetricians, with the opportunity for evaluation and education afterwards.
Further consideration needs to be given to how regulations can be revised in a way that ensures that healthcare improvement activities using the same quality data in Switzerland are not either overregulated on one side or completely without control on the other.
Adaptation of cost-effectiveness analyses to a single country: the case of bariatric surgery for obesity and overweight
There is a relatively broad international literature on the cost effectiveness of bariatric surgery, but no systematic reviews that examine the transferability of international cost-effectiveness results for Switzerland or another single country.
Shared decision-making for prostate cancer screening and treatment: a systematic review of randomised controlled trials
Men facing prostate cancer screening and treatment need to make critical and highly preference-sensitive decisions that involve a variety of potential benefits and risks. Shared decision-making is considered fundamental for “preference-sensitive” medical decisions.
Funding characteristics of randomised clinical trials supported by the Swiss National Science Foundation: a retrospective cohort study
Failure to publish publicly funded research represents a waste of scarce research resources. In Switzerland, about 40% of randomised clinical trials supported by the Swiss National Science Foundation were not published.
There is urgent need for further research and development in the fields of musculoskeletal rehabilitation.
Could it be that legislators and other public health professional base their tobacco control policy decisions on smoking prevalence estimates that are more reassuring than may be justified?