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Optimal allocation of limited test resources for the quantification of COVID-19 infections
The proposed methodology can lead to vastly less uncertain predictions for the spread of the disease, thus improving estimates of the effective reproduction number and the future number of unreported infections. This information can provide timely and systematic guidance for the effective identification of infectious individuals and for decision-making regarding lockdown measures and the distribution of vaccines.
37-year incidence and mortality time trends of common cancer types by sex, age, and stage in the canton of Zurich
The Cancer Registry Zurich, Zug, Schaffhausen and Schwyz is one of the oldest cancer registries in Switzerland, first registering tumours in 1980 for the canton of Zurich. The aim of this study was to analyse trends in incidence and mortality for the most common types of cancer in the canton of Zurich from 1981 to 2017.
Flattening the curve in 52 days: characterisation of the COVID-19 pandemic in the Principality of Liechtenstein – an observational study
The close collaboration of all relevant stakeholders allowed for the complete workup of all COVID-19 patients nationwide. A multitude of factors led to the early containment of the first wave of the pandemic, with a very low rate of serious outcomes. Antibody testing for SARS-CoV-2 revealed a substantial proportion of undiagnosed COVID-19 cases among close contacts of the patients.
COVID-19 infectivity profile correction
Presymptomatic infections are spread over a longer time period before symptom onset than previously thought, which can have significant ramifications for contact tracing efforts.
A research agenda for digital proximity tracing apps
It is likely that there is only a limited time window for the optimisation of the proximity tracing app and promotion of substantial population uptake. It will be all the more important that research programmes allow data-driven, evidence-based optimisations, and information for the public about the benefits, harms and costs of proximity tracing apps.
Assessing the impact of non-pharmaceutical interventions on SARS-CoV-2 transmission in Switzerland
Current estimates of time-varying R0 in Switzerland well below one are promising. However, as of 24 April 2020, at least 96% of the Swiss population remains susceptible to SARS-CoV-2. These results warrant a cautious relaxation of social distance practices and close monitoring of changes in both the basic and effective reproduction numbers.
Time trend of suicide in Swiss male farmers and comparison with other men: a cohort study
The ongoing agricultural reforms present serious challenges for Swiss farmers. This study shows a higher rate of suicide in farmers compared to non-farmers in Switzerland, with the gap widening increasingly after 2006.
Early off-label treatment during pandemics? A dilemma
Decisions for or against off-label treatment need to be based on clearly defined selection and treatment criteria, a strong biological rationale, a critical appraisal of prior evidence, and the estimated harm-benefit ratio.
icumonitoring.ch: a platform for short-term forecasting of intensive care unit occupancy during the COVID-19 epidemic in Switzerland
In Switzerland, the COVID-19 epidemic is progressively slowing down owing to “social distancing” measures introduced by the Federal Council on 16 March 2020. However, the gradual ease of these measures may initiate a second epidemic wave, the length and intensity of which are difficult to anticipate. The authors introduce icumonitoring.ch, a platform providing hospital-level projections for ICU occupancy.
Reproductive number of the COVID-19 epidemic in Switzerland with a focus on the Cantons of Basel-Stadt and Basel-Landschaft
The reproductive number in Switzerland was between 1.5 and 2 during the first third of March, and has consistently decreased to around 1. After the announcement of the latest strict measure on 20 March 2020, namely that gatherings of more than five people in public spaces are prohibited, the reproductive number dropped significantly below 1; the authors of this study estimate the reproductive number to be between 0.6 and 0.8 in the first third of April.
