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Use of SGLT2 inhibitors in cardiovascular diseases: why, when and how?

Review article: Biomedical intelligence
Lu H, Meyer P, Hullin R
Swiss Med Wkly. 2020;150:w20341

The authors present an up-to-date narrative literature review of the physiological mechanisms of action, current indications, therapeutic utility and side effects of SGLT2 inhibitors.

Effect of guideline revisions by the Swiss Society of Hypertension on blood pressure control in hypertensive patients from primary care

Original article
Giezendanner S, Tschudi P, Leuppi J, Dieterle T, Zeller A
Swiss Med Wkly. 2020;150:w20279

The 2009 guideline change in high-risk patients was associated with a reduction in systolic office blood pressure together with an increase in pharmacological combination therapy. These results highlight primary care physicians’ efforts to implement blood pressure guidelines. Further, blood pressure goal attainment was more likely to be achieved in later follow-up visits.

Coronary and structural heart interventions in Switzerland 2018

Original article
Nestelberger T, Twerenbold R, Cook S, Gaemperli O, Meier P, Mueller O, Nietlisbach F, Raeber L, Weilenmann D, Jeger R
Swiss Med Wkly. 2020;150:w20200

Since 1987, based on a standardised questionnaire that has evolved over the years, all Swiss cardiology centres are asked to report yearly aggregate data on the number and type of percutaneous cardiac procedures performed.

Marfan syndrome and related connective tissue disorders in the current era in Switzerland in 103 patients: medical and surgical management and impact of genetic testing

Original article
Bombardieri E, Rohrbach M, Greutmann M, Matyas G, Weber R, Radulovic J, Fasnacht Boillat M, Linka A, De Pasquale G, Bonassin F, Attenhofer Jost CH
Swiss Med Wkly. 2020;150:w20189

Marfan syndrome (MFS) and related connective tissue disorders (CTDs) are increasingly recognised. Genetic testing has greatly improved the diagnostic outcome/power over the last two decades.

Atrial fibrillation for internists: current practice

Review article: Biomedical intelligence
Meyre P, Conen D, Osswald S, Kühne M, Meyer-Zürn C
Swiss Med Wkly. 2020;150:w20196

Atrial fibrillation is the most common sustained cardiac arrhythmia in clinical practice, and its prevalence is expected to increase in the near future.

Plaque vulnerability in patients with high- and moderate-grade carotid stenosis – comparison of plaque features on MRI with histopathological findings

Original article
Tapis P, El-Koussy M, Hewer E, Mono ML, Reinert M
Swiss Med Wkly. 2020;150:w20174

Plaque vulnerability plays an important role in determining the risk of subsequent cerebrovascular events in patients with carotid stenosis. Plaque morphology magnetic resonance imaging (MRI) can be used to assess plaque vulnerability.

Fiftieth anniversary of the first heart transplantation in Switzerland in the context of the worldwide history of heart transplantation

Review article: Biomedical intelligence
Wilhelm MJ, Ruschitzka F, Flammer AJ, Bettex D, Turina MI, Maisano F
Swiss Med Wkly. 2020;150:w20192

To commemorate the 50th anniversary of the first heart transplantation in ­Switzerland, on 14 April 1969, this article reviews the history of the procedure worldwide and current challenges.

Duration of pharmacological thromboprophylaxis after outpatient endovenous laser ablation: a propensity score-matched analysis

Original article
Keo HH, Spinedi L, Staub D, Diehm N, Holtz D, Broz P, Regli C, Uthoff H
Swiss Med Wkly. 2019;149:w20166

Many centres in Europe, including several in Switzerland, use pharmacological thromboprophylaxis after thermal ablation of varicose veins. However, the optimal duration of pharmacological thromboprophylaxis is currently not defined.

Role of imaging in primary prevention: calcium score is a robust and cost-efficient risk modifier

Viewpoint
Yakupoglu HY, Gräni C
Swiss Med Wkly. 2019;149:w20183

Subclinical atherosclerosis, assessed by imaging, is associated with outcome. Imaging has the potential to enable providers to better tailor preventive therapy towards patient risk stratification compared to traditional risk scores.

First in Switzerland: concomitant off-pump transapical transcatheter aortic valve implantation and mitral valve reconstruction with the NeoChord system

Original article
Ntinopoulos V, Tüller D, Bernheim A, Papadopoulos N, Haeussler A, Matter-Ensner S, Eberli F, Dzemali O
Swiss Med Wkly. 2019;149:w20168

Older and polymorbid patients with multivalvular heart disease exhibit high peri­operative morbidity and mortality when treated with conventional surgery. Minimally invasive concomitant procedures are, however, possible.

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