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Immunosuppressant therapeutic drug monitoring and trough level stabilisation after paediatric liver or kidney transplantation
Immunosuppressive therapy must be guided by therapeutic drug monitoring (TDM) in paediatric liver (LT) and kidney transplantation (KT) patients to prevent under- and overdosing, which have clinical consequences.
A simple guide to the interpretation of the significance of the association of a disease with a particular HLA allele
The impressive survival advantage of the adaptive immune system comes at the cost of autoimmunity and autoimmune disease because of the self-selected character of the adaptive immune system’s T cell repertoires.
Behçet’s syndrome is a rare systemic autoimmune/autoinflammatory disease. In Switzerland there are no published data regarding the prevalence of Behçet’s syndrome, its manifestations or its management.
Chronic rhinosinusitis in unified airway disease: surfactant proteins as mediators of respiratory immunity
Management of chronic rhinosinusitis and asthma must be jointly carried out as one functional entity.
Design and evaluation of a multi-epitope assembly peptide vaccine against Acinetobacter baumannii infection in mice
Multi-epitope assembly peptides, which contain B-cell epitopes, T-cell epitopes or other specific residues, have been proved to be promising vaccine candidates against several pathogens in animal models.
Owing to its different but proven mode of action, interleukin-2 immunotherapy could complement many anticancer approaches, including immune checkpoint inhibitors, adoptive cell transfer regimens and vaccination.
Vocal cord dysfunction is characterised by paradoxical inspiratory laryngeal motion and is often misdiagnosed as asthma. Diagnosis is difficult, because laryngoscopy is positive only during symptomatic episodes or provocation tests.
The occurrence and development of cancer cells in the body is a dynamic process of interaction between the immune system and the tumour cells. Whether tumour growth is promoted or suppressed in the parabiosis model is still unclear.
The manifestations of giant cell arteritis can be variable. About a third of large-vessel giant cell arteritis patients have no sonographic evidence of temporal vasculitis, and more than half have normal histology of the temporal artery.
Diffuse large B-cell lymphoma chemotherapy reveals a combined immunodeficiency syndrome in cartilage hair hypoplasia
Cartilage hair hypoplasia is a rare autosomal recessive ribosomopathy related to a mutation in the ribonuclease mitochondrial RNA processing (RMRP) gene, which encodes the mitochondrial portion of the RNA processing endonuclease.