Cancer cells are dependent on a few driver genes for the constitutive activation of the signalling pathways which aid cellular proliferation. Targeting oncogenic-dependent genes has met with success, as demonstrated in several cancer types.
Although the aetiology of systemic sclerosis is not yet completely understood, epidemiological studies have identified several occupational factors, such as exposure to silica, solvents or vibration, that contribute to its development.
Working in a hospital can be both rewarding and stressful. Whether one or the other is dominant depends on a number of factors ranging from shift work, physical demands, responsibilities and time pressure to job autonomy, work climate and leisure time.
Frozen shoulder is a poorly understood pathological entity which is characterised by a painful and stiff shoulder. No current epidemiological data with respect to frozen shoulder-induced direct and indirect costs to the Swiss national healthcare system are available.
Plaque vulnerability plays an important role in determining the risk of subsequent cerebrovascular events in patients with carotid stenosis. Plaque morphology magnetic resonance imaging (MRI) can be used to assess plaque vulnerability.
SMW is an international peer-reviewed medical journal, established in 1871.
Public Service Open Access is also known als Diamond or Platinum OA.
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