Prevalence of genetic susceptibility for breast and ovarian cancer in a non-cancer related study population: secondary germline findings from a Swiss single centre cohort

Since the advent of high-throughput sequencing technologies, organised germline screening, independent of personal and family cancer history, has been frequently proposed. A critical prerequisite is knowledge of the expected carrier frequencies.

Prevalence of high-risk drug-drug interactions in paediatric inpatients: a retrospective, single-centre cohort analysis

Drug-drug interaction (DDI) screening programmes aim to increase the safety of medication by issuing alerts based on the severity of DDIs. However, not all DDI alerts may be clinically relevant.