Synovial sarcoma: when epigenetic changes dictate tumour development

Synovial sarcoma accounts for 10 to 20% of all soft tissue sarcomas in the adolescent and young adult population and is the most common soft tissue sarcoma after rhabdomyosarcoma. Elucidation of the pathogenesis is needed to develop effective, mechanism-based therapeutic strategies.

Dual use in the 21st century: emerging risks and global governance

Dual use risks in the second decade of the 21st century are characterised by: diversification of dual use domains, digitalisation of potential threats, and the proliferation of actors.

Motivational interviewing increases autopsy rates

Autopsies are a crucial source of medical knowledge. Autopsy rates have decreased in Switzerland and many other countries. Communication between clinicians and the deceased’s sceptical relatives is crucial to obtain autopsy permission.

A community outbreak of Legionnaires' disease in Geneva, Switzerland, June to September 2017

Eight confirmed cases of Legionnaires’ disease were identified at the Geneva University Hospitals between 28 July 2017 and 02 August 2017, leading to the detailed outbreak investigation reported here.

Does seminal vesicle-sparing robotic radical prostatectomy influence postoperative prostate-specific antigen measured with an ultrasensitive immunoassay?

The authors analysed whether sparing of the seminal vesicles during robotic radical prostatectomy affects oncological outcome in terms of ultrasensitive PSA nadir and biochemical recurrence as compared with standard robotic assisted laparoscopic radical prostatectomy.

Medical-ethical guidelines: Management of dying and death

Provision of treatment, care and support for patients who are facing death is a key medical duty, requiring a high degree of respect for the patient’s dignity and autonomous wishes, and considerable ethical responsibility.