Swiss Medical Weekly congratulates Jaco van Rheenen, recipient of the Dr Josef Steiner Cancer Research Foundation Award for 2017

Prof. Dr Jacco van Rheenen was recognized for his groundbreaking research delineating the dynamics of tumor cell invasion and metastasis in mouse models of cancer, via the development of fluorescent imaging tools that enable the visualization of cancer cell movements in real time in primary tumors and metastatic sites.

Does interprofessionality work in Swiss ICUs and should it be encouraged?

The intensive care unit (ICU) is a complex universe, with high intensity of care and emotional stress. With the critically ill patient at the centre, all members of the ICU team must learn how to work together.

Role of liver magnetic resonance imaging in hyperferritinaemia and the diagnosis of iron overload

Accurate evaluation and monitoring of iron overload has major implications regarding prognosis and quality of life. MRI can evaluate the presence of iron overload and aid the detection of underlying conditions.

Cellular protection mechanisms that minimise accumulation of mutations in intestinal tissue

The very dynamic nature of the intestinal epithelium results in three cellular ­protection mechanisms that minimise the accumulation of new mutations in the intestine, thereby protecting against aging and development of colorectal cancer.

Cost-effectiveness of sacubitril/valsartan in chronic heart-failure patients with reduced ejection fraction

Sacubitril/valsartan, an angiotensin-receptor-neprilysin-inhibitor, is a novel oral therapy proposed in the current guidelines for the treatment of heart failure in patients with reduced left ventricular ejection fraction.

Temporal trends of postpartum haemorrhage in Switzerland: a 22-year retrospective population-based cohort study

Postpartum haemorrhage is one of the leading causes of maternal morbidity and mortality. An increase in incidence of postpartum haemorrhage in recent years has been reported.

Ultrasound indications for maternal STORCH testing in pregnancy

Fetal abnormalities found on ultrasonography lead to a variety of diagnostic procedures, including a panel of tests to detect possible maternal STORCH infections.

Informal caregiving, work-privacy conflict and burnout among health professionals in Switzerland - a cross-sectional study

Burnout is a stress-induced illness that often occurs in healthcare and other human service professionals. Work-privacy conflict has been found to be a stronger predictor of burnout than work-specific stressors.

Risk behaviours among native and immigrant youths in Switzerland: a cross-sectional study

Switzerland has been receiving migrants of various origins for more than 50 years, but the adoption of risk-taking behaviours among migrant youths is unclear.

Insufficient recruitment and premature discontinuation of clinical trials in Switzerland: qualitative study with trialists and other stakeholders

Premature discontinuation occurs in about 25% of randomised clinical trials in Switzerland; it mainly affects investigator-initiated trials and is mostly due to problems with recruitment of patients.

Hepatitis C virus dynamics among intravenous drug users suggest that an annual treatment uptake above 10% would eliminate the disease by 2030

Timely treatment of hepatitis C virus among people who inject drugs is necessary to reduce the prevalence and prevent new infections in Switzerland.

Safety and effectiveness of labour induction after caesarean section using balloon catheter or oxytocin

Induction of labour after previous caesarean section is challenging owing to the increased risk of uterine rupture. The effectiveness of balloon catheters and oxytocin as labour inducers remains unclear as currently available data are limited.

Precision medicine for monogenic diabetes: from a survey to the development of a next-generation diagnostic panel

Monogenic diabetes most frequently presents as maturity onset diabetes of the young (MODY), an autosomal dominant disorder leading to beta cell dysfunction.