Challenges of congenital heart disease in grown-up patients

Cardiac defects are the most common birth defect and affect approximately 0.8% of newborns. Over the past 70 years there has been a remarkable increase in survival of children with congenital heart disease.

Outcomes, rates and predictors of transition of isolated Raynaud’s phenomenon: a systematic review and meta-analysis

Primary Raynaud’s phenomenon is generally a benign condition, but some population-based studies suggest that secondary Raynaud’s phenomenon develops in 12 to 20% of subjects first diagnosed with the primary condition.

Adolescents’ contraception continuation in Switzerland: a prospective observational study

As risks of unintended pregnancy increase with every change of contraceptive method, this study aimed to measure continuity with contraception among adolescents, and factors that influence it.

Factors associated with cessation of smoking among Swiss adults between 1991 and 2011: results from the SAPALDIA cohort

A nation-wide smoking ban in public places was enforced in Switzerland in 2010. But less is known about personal factors influencing the likelihood of smoking cessation.

Survival from methicillin-sensitive Staphylococcus aureus bloodstream infections over 20 years: a cohort of 1328 patients

This study was performed in a unique setting – an institution with with a very low prevalence of MRSA, which provided the opportunity to report from an almost homogenous methicillin-sensitive Staphylococcus aureus cohort.

Quality of vitamin K antagonist oral anticoagulation in 322 patients with atrial fibrillation – real-life data from a survey in Eastern Switzerland

Effective and safe oral anticoagulation can be achieved by use of a vitamin K antagonist with a high time in the therapeutic range. However, several studies have shown that in clinical practice time in the therapeutic range is less than optimal.