Rejuvenation is an old dream of an ageing humankind.
The authors give an overview of what is known about prion architecture and how the limited structural information available has been used in the quest for remedies for these devastating disorders.
Pulmonary hypertension associated with COPD and interstitial lung disease is common but difficult to manage.
The aim of this study was to assess the efficacy and safety of DOACs in elderly patients (aged 75 years or more) with atrial fibrillation or venous thromboembolism (VTE), based on already published large randomised trials.
Although sentinel lymph node biopsy is the most sensitive and accurate investigative modality for establishing regional node status in patients with melanoma, its role and benefit in melanoma of different Breslow’s thickness is still controversial.
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