Multidisciplinary approach for risk-oriented treatment of low-risk papillary thyroid cancer in Switzerland

With the intention to find a common view on the management of patients with low-risk papillary thyroid cancer (PTC), a multidisciplinary working group was initiated by the Swiss Society for Endocrinology and Diabetes and endorsed by the Swiss Society for Nuclear Medicine and the working group of Swiss Endocrine Surgeons.

A new era of gene editing for the treatment of human diseases

Significant advances in the field of gene editing have not only provided new tools for genetic surgery, but have also heralded a new era of medicine, with possibilities never imagined even half a century ago.

Vascular endothelial growth factor biology for regenerative angiogenesis

Therapeutic angiogenesis can lead to arteriogenesis and so restore tissue perfusion, but a more comprehensive understanding of the complex underlying biology is required to significantly improve the efficacy of such treatment strategies.

Development of a novel class of interleukin-2 immunotherapies for metastatic cancer

Owing to its different but proven mode of action, interleukin-2 immunotherapy could complement many anticancer approaches, including immune checkpoint inhibitors, adoptive cell transfer regimens and vaccination.

Liquid biopsy in tissue-born lymphomas

“Liquid biopsy” in lymphoma types lacking leukaemic involvement refers to the accessing of tumour-specific DNA in plasma, serum or other body fluids, without the necessity of an invasive tumour biopsy.

Use of coronary computed tomography angiography in clinical practice – single centre experience in Switzerland in light of current recommendations based on pretest probability considerations

The results of this study suggest a very judicious use of coronary computed tomography angiography as a gatekeeper for invasive coronary angiography in current practice.

Impact of experience in breast cancer surgery on survival: the role of quality of care in a registry-based cohort

Previous studies have suggested that the surgeon’s experience in breast cancer surgery may affect patient survival. However, why the surgeon’s experience could influence breast cancer mortality remains unclear.

Microelimination of chronic hepatitis C in Switzerland: modelling the Swiss Hepatitis Strategy goals in eastern, western and northern regions

The Swiss Hepatitis Strategy aims to eliminate hepatitis C virus infection and associated liver-related morbidity and mortality by 2030. To date, Little has been done to identify the epidemiology of HCV on the regional, or micro, level.

Trends in influenza vaccination uptake in Switzerland: Swiss Health Survey 2007 and 2012

In Switzerland, there is no information on trends in influenza vaccine uptake at a national level to improve the vaccine uptake and guide future vaccination programmes.