Bacterial genome sequencing and analysis: paving the way for a Switzerland-wide molecular epidemiological surveillance platform

The proposal to establish a national platform where bacterial isolates from all corners of Switzerland can be assembled and compared against each other in a standardised, reproducible way can be read as a manifesto for extracting a maximum of microbiological information and delivering it in a timely fashion.

The hypoxic kidney: pathogenesis and noncoding RNA-based therapeutic strategies

Acute kidney injury is a disease entity of major importance, affecting approximately 6% of all patients on the intensive care unit. Novel markers and knowledge of their pathophysiological role is of major importance for targeted therapeutic interventions. Noncoding RNAs have recently been introduced and are the subject of intensive research initiatives.

The Swiss Primary Ciliary Dyskinesia registry: objectives, methods and first results

Centralised collection of data in national and international registries is essential to raising patient numbers in the epidemiological study of rare diseases such as primary ciliary dyskinesia, and filling in gaps in knowledge.