Nowadays we typically use patient experience as a quality of care indicator, although this has some limitations. However, the findings are somewhat inconsistent or even conflicting.
Arteriovenous malformations are characterised by an abnormal connection between arteries and veins, bypassing the capillary system. Management modalities are observation, microsurgical clipping, endovascular treatment and radiosurgery.
The authors propose that all suitable Phe508del homozygous cystic fibrosis patients with end-stage pulmonary disease should have a trial of LUM/IVA treatment in experienced centres.
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