Skip to main navigation menu Skip to main content Skip to site footer

Original article

Vol. 146 No. 4546 (2016)

Novel cases of amyotrophic lateral sclerosis after treatment of cerebral arteriovenous malformations

  • Michael Linnebank
  • Cameron G. McDougall
  • Stefanie Krueger
  • Saskia Biskup
  • Manuela Neumann
  • Michael Weller
  • Antonios Valavanis
  • Johannes Prudlo
DOI
https://doi.org/10.4414/smw.2016.14361
Cite this as:
Swiss Med Wkly. 2016;146:w14361
Published
06.11.2016

Summary

Previous case studies reported nine patients with cerebral arteriovenous malformations (AVM) who developed amyotrophic lateral sclerosis (ALS) after AVM embolisation. Here, we describe three novel cases of ALS which developed 13–34 years after treatment, including embolisation, of cerebral AVM. This study provides further arguments supporting the thesis that embolisation of cerebral AVM might influence the risk of later ALS development.

References

  1. Valavanis A, Schwarz U, Baumann CR, Weller M, Linnebank M. Amyotrophic lateral sclerosis after embolization of cerebral arterioveneous malformations. J Neurol. 2014;261:732–7.
  2. Kim GH, Hahn DK, Kellner CP, Hickman ZL, Komotar RJ, et al. Plasma levels of vascular endothelial growth factor after treatment for cerebral arteriovenous malformations. Stroke. 2008;39:2274–9.
  3. Brooks BR, Miller RG, Swash M, Munsat TL. El Escorial revisited: revised criteria for the diagnosis of amyotrophic lateral sclerosis. Amyotroph Lateral Scler Other Motor Neuron Disord. 2000;1:293–9.
  4. Katsavarou O, Ntampos S, Sarmas I, Triantafyllou N, Giannopoulos S, Kyritsis AP. Embolization treatment of cerebral arteriovenous malformations and amyotrophic lateral sclerosis. Neurol Sci. 2015;36:483–4.
  5. Turner MR, Goldacre R, Talbot K, Goldacre M. Cerebrovascular injury as a risk factor for amyotrophic lateral sclerosis. J Neurol Neurosurg Psychiatry. 2016;87:244–6.

Most read articles by the same author(s)