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Review article: Biomedical intelligence

Vol. 143 No. 0910 (2013)

Nanomaterials and the human lung: what is known and what must be deciphered to realise their potential advantages?

  • Corinne Jud
  • Martin James David Clift
  • Alke Petri-Fink
  • Barbara Rothen-Rutishauser
DOI
https://doi.org/10.4414/smw.2013.13758
Cite this as:
Swiss Med Wkly. 2013;143:w13758
Published
24.02.2013

Summary

Due to the constant expansion within the nanotechnology industry in the last decade, nanomaterials are omnipresent in society today. Nanotechnology-based products have numerous different applications ranging from electronic (e.g., advanced memory chips) to industrial (e.g., coatings or composites) to biomedical (e.g., drug delivery systems, diagnostics). Although these new nanomaterials can be found in many “everyday” products, their effects on the human body have still to be investigated in order to identify not only their risk, but also their potential benefits towards human health. Since the lung is commonly thought to be the main portal of entry into the human body for nanomaterials released within the environment, this review will attempt to summarise the current knowledge and understanding of how nanomaterials interact with the respiratory tract. Furthermore, the advantages and disadvantages of different experimental model systems that are commonly used to study this exposure route to the human body will be discussed.

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