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Review article: Biomedical intelligence

Vol. 142 No. 1920 (2012)

Systemic-onset juvenile idiopathic arthritis: the changing life of a rare disease

  • Rolando Cimaz
  • Annette Von Scheven
  • Michael Hofer
DOI
https://doi.org/10.4414/smw.2012.13582
Cite this as:
Swiss Med Wkly. 2012;142:w13582
Published
06.05.2012

Summary

Systemic-onset juvenile idiopathic arthritis (SoJIA), sometimes called Still’s disease, is a systemic inflammatory disease classified within the spectrum of juvenile idiopathic arthritis (JIA). It is an orphan disease with often a chronic course and a major impact on the affected children and their families. This disorder is unique in terms of clinical manifestations, prognosis and response to conventional immunosuppressants. The objectives of this review are to describe SoJIA and emphasise the recent advances in the pathogenesis and treatment, which have transformed the care and the prognosis of this potentially life-threatening paediatric condition.

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