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Original article

Vol. 140 No. 3334 (2010)

Premature deaths in Switzerland from 1995–2006: causes and trends

  • A Savidan
  • S Ess
DOI
https://doi.org/10.4414/smw.2010.13077
Cite this as:
Swiss Med Wkly. 2010;140:w13077
Published
16.08.2010

Summary

Purpose: Mortality expressed as potential years of life lost (PYLL) underscores premature and preventable mortality. We analysed causes of and trends in premature death in Switzerland to highlight the areas which provide the greatest potential outcome for preventive measures.

Methods: Premature mortality rates and trends from 1995–2006 were examined by reviewing potential years of life lost between age 1 and 70, as the upper age limit, considering 4 main categories: circulatory diseases, cancer, external causes of mortality and other causes, and 19 specific causes of death. Trends were assessed using join point analysis with PYLL expressed as age-standardised rate. The analysis was based on the official death certification files provided by the Swiss Federal Statistical Office.

Results: Age adjusted PYLL rates decreased for all categories of causes, but the decline in cancers was modest compared to circulatory diseases and external causes. The strongest downward trends were observed for AIDS, traffic accidents and ischaemic heart disease. In women breast cancer contributed most to the decline of premature mortality but remains the first cause of early death. Lung cancer in women is the only cause of premature mortality with rising trends.

Conclusions: Past efforts in prevention, early detection and treatment, but also a healthier lifestyle and other factors, have very probably contributed to the considerable reduction in the rate of potential years of life lost, but the rising rate of premature mortality caused by lung cancer in women is of concern. Persistent efforts in prevention and early detection are required to further reduce premature death and its burden on society.

References

  1. Gardner JW, Sanborn JS. Years of potential life lost (YPLL) – what does it measure? Epidemiology. 1990;1:322–9.
  2. Romeder JM, McWhinnie JR. Potential years of life lost between ages 1 and 70: an indicator of premature mortality for health planning. Int J Epidemiol. 1977;6:143–51.
  3. Rask K, O’Malley E, Druss B. Impact of socioeconomic, behavioral and clinical risk factors on mortality. J Public Health. (Oxf) 2009;31:231–8.
  4. Murray CJ, Lopez AD. Alternative projections of mortality and disability by cause 1990–2020: Global Burden of Disease Study. Lancet. 1997;349:1498–504.
  5. Peto R, Lopez AD, Boreham J, et al. Mortality from tobacco in developed countries: indirect estimation from national vital statistics. Lancet. 1992;339:1268–78.
  6. Richtlinien für die ärztliche Bescheinigung der Todesursachen. In Statistics FOf (ed) Edition Bern, Switzerland: Bundesamt für Statistik 1996; 1–60.
  7. WHO. International Statistical Classification of Diseases and related Health Problems: 10th Revision. In Edition Geneva, Switzerland: World Health Organisation 1994.
  8. Lutz JM, Pury P, Fioretta G, Raymond L. The impact of coding process on observed cancer mortality trends in Switzerland. Eur J Cancer Prev. 2004;13:77–81.
  9. Cancer incidence in five continents. IARC Sci Publ. 1976;1–583.
  10. StataCorp. 2007. Stata Statistical Software: Release 10. College Station, TX: StataCorp LP
  11. Joinpoint Regression Program, Version 3.4 – September 2009; Statistical Research and Applications Branch, National Cancer Institute.
  12. NCI. Join point Regression programme. Version 3.3 Software produced by the statistical research and application branch, National Cancer Insititute, Silver Springs US. In http://srab.cancer.gov/, Edition 2008.
  13. Kim H, Foy MP, Fewer EJ, Midthune DN. Permutation tests for join point regression with applications to cancer rates. Stat Med. 2000;19:335–51.
  14. Kim HJ, Fay MP, Yu B, et al. Comparability of segmented line regression models. Biometrics. 2004;60:1005–14.
  15. Colin M, Thies B, Doris MF. Global burden of Disease: update 2004. In Edition World Health Organisation 2004.
  16. Wigle DT, Mao Y, Semenciw R, et al. Premature deaths in Canada: impact, trends and opportunities for prevention. Can J Public Health. 1990;81:376–81.
  17. Wheller L, Baker A, Griffiths C. Trends in premature mortality in England and Wales, 1950–2004. Health Statistics Quarterly 2006;34–41.
  18. Wiesner G, Casper W. Changes in suicide mortality in Germany. Gesundheitswesen. 1993;55:367–71.
  19. Guberan E. Mortality trends in Switzerland 1951–1977. Principal categories of the causes of death. Schweiz Med Wochenschr. 1979;109:1465–71.
  20. Berrut S, Junker C. Von Generation zu Generation. In BFS BfS (ed) Statistik der Schweiz, Edition Neuchatel, Switzerland: 2008.
  21. Levi F, Lucchini F, Negri E, La Vecchia C. Trends in mortality from major cancers in the European Union, including acceding countries, in 2004. Cancer. 2004;101:2843–50.
  22. Levi F, Bosetti C, Fernandez E, et al. Trends in lung cancer among young European women: the rising epidemic in France and Spain. Int J Cancer. 2007;121:462–5.
  23. La Vecchia C, Bosetti C, Lucchini F, et al. Cancer mortality in Europe, 2000–2004, and an overview of trends since 1975. Ann Oncol. 2009.
  24. Bulliard JL, La Vecchia C, Levi F. Diverging trends in breast cancer mortality within Switzerland. Ann Oncol. 2006;17:57–9.
  25. Stolt Steiger V, Goy JJ, Stauffer JC, et al. Significant decrease in in-hospital mortality and major adverse cardiac events in Swiss STEMI patients between 2000 and December 2007. Swiss Med Wkly. 2009;139:453–7.
  26. Meyer K, Murner N, Laederach-Hofmann K, et al. Heart failure events, and case fatalities in Switzerland based on hospital statistics and cause of death statistics. Swiss Med Wkly. 2008;138:506–11.
  27. Niemann S, Fahrni S, Brügger O, Cavegn M. Unfallgeschehen in der Schweiz: bfu-Statistik 2008. Bern: bfu; 2008.
  28. Ezzati M, Hoorn SV, Rodgers A, et al. Estimates of global and regional potential health gains from reducing multiple major risk factors. Lancet. 2003;362:271–80.
  29. Tyczynski JE, Bray F, Parkin DM. Lung cancer in Europe in 2000: epidemiology, prevention, and early detection. Lancet Oncol. 2003;4:45–55.
  30. Kuntsche S, Gmel G. The smoking epidemic in Switzerland – an empirical examination of the theory of diffusion of innovations. Soz Praventivmed. 2005;50:344–54.
  31. Parkin DM, Chen VW, Ferlay J, et al. Comparability and Quality control in Cancer Registration. In IARC (ed) IARC Technical Report No. 19, Edition Lyon: IARC 1994.
  32. Lai D, Hardy RJ. Potential gains in life expectancy or years of potential life lost: impact of competing risks of death. Int J Epidemiol. 1999;28:894–8.
  33. Blane D, Drever F. Inequality among men in standardised years of potential life lost, 1970–93. BMJ. 1998;317:255–6.
  34. Blane D, Smith GD, Bartley M. Social class differences in years of potential life lost: size, trends, and principal causes. BMJ. 1990;301:429–32.