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Review article: Biomedical intelligence

Vol. 140 No. 2930 (2010)

Cathepsins and their involvement in immune responses

  • S Conus
Cite this as:
Swiss Med Wkly. 2010;140:w13042


The immune system is composed of an enormous variety of cells and molecules that generate a collective and coordinated response on exposure to foreign antigens, called the immune response. Within the immune response, endo-lysosomal proteases play a key role. In this review we cover specific roles of cathepsins in innate and adaptive immunity, as well as their implication in the pathogenesis of several diseases.


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