Primary brainstem haemorrhages remain associated with poor outcomes compared to other forms of spontaneous intracranial haemorrhage. Their management needs re-evaluation and reinvestigation to update the relevant data.
Hopes are very high that drones will provide extraordinary help to emergency response teams. On the other hand, critics are concerned about the real value of this technology.
Tissue engineering approaches in a paediatric population are particularly relevant because of the critical need for transplant material and the small amount of accessible autologous graft tissue.
Major improvements in biotechnology and bioinformatics have been achieved over the past two decades, allowing the development of omic signatures of several molecular subtypes of cancer, each associated with different outcomes.
The recent increase in knowledge about multiple myeloma necessitated an update of the guidelines published 3 years ago.
Combination anti-retroviral therapy (cART) has reduced mother-to-child transmission (MTCT) and improved the prognosis of HIV-infected newborns. However, drug resistance mutations (DRM) either transmitted by MTCT (HIV-tDRM) or selected by suboptimal adherence and drug levels (HIV-sDRM) remain a concern.
Knowledge of the positive predictors for Chagas disease is important to better target screening for the highest risk population. Another important element in the design of an effective screening strategy is the type of diagnostic test to be used.
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