Acute kidney injury is a disease entity of major importance, affecting approximately 6% of all patients on the intensive care unit. Novel markers and knowledge of their pathophysiological role is of major importance for targeted therapeutic interventions. Noncoding RNAs have recently been introduced and are the subject of intensive research initiatives.
Current tobacco control legislation in Switzerland is based on a “one-size-fits-all” approach in linguistic terms. This is inappropriate given that there are seven Cantons where German is not the primary language.
What relevant research and health problems can only be addressed by a sufficiently large Swiss citizen study comparable to All of Us or other equivalent initiatives in Europe and across the globe?
Experiencing and integrating one’s own feelings and needs
The proposal to establish a national platform where bacterial isolates from all corners of Switzerland can be assembled and compared against each other in a standardised, reproducible way can be read as a manifesto for extracting a maximum of microbiological information and delivering it in a timely fashion.
The rationale of seminal vesicle sparing robotic radical prostatectomy is to spare nerves that are responsible for erectile function and close to the tips of the seminal vesicles. However, these remaining tips are known to produce prostate-specific antigen, which is measured for postoperative monitoring.
The introduction of a country-wide molecular surveillance database aims to increase the overall whole genome sequencing data quality and establish a molecular surveillance platform for selected pathogens.
Centralised collection of data in national and international registries is essential to raising patient numbers in the epidemiological study of rare diseases such as primary ciliary dyskinesia, and filling in gaps in knowledge.
A new generation of physicians, millennials (also known as Generation Y), are entering residency programmes in internal medicine, and these young men and women learn and work in ways that are different from those of past generations.
Allostatic load, a marker of cumulative stress, is associated with higher morbidity and mortality, and reduced health-related quality of life in healthy adults. In patients with hypertension this association has not been investigated.
Injury prevention in amateur soccer has been promoted in recent years, but few studies have addressed long-term changes in injury rates. Better knowledge of changes in injury incidences and causes could help improve prevention strategies.
The diagnostic diversity index can be seen as an indicator of diagnostic precision - the higher the degree of diversity, the better the diagnostic precision.
Vocal cord dysfunction is characterised by paradoxical inspiratory laryngeal motion and is often misdiagnosed as asthma. Diagnosis is difficult, because laryngoscopy is positive only during symptomatic episodes or provocation tests.
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